Function and principle of bone marrow cell counter

The function of the bone marrow cell counter is to observe the morphology, quantity and distribution of bone marrow cells, and it is one of the important methods for diagnosing blood system diseases.

The number of various bone marrow cells, such as granulocytes, erythroid cells and lymphocytes/monocytes, can be observed in the counter; at the same time, the different distribution conditions of different cells, such as proliferation, necrosis, maturation, etc. can also be observed.

The principle of bone marrow cell counter is mainly based on microscope and counting chamber.

1. Microscope: Bone marrow sections are usually observed and counted under a microscope. Using a high-power microscope, various cells in the bone marrow can be observed, such as primitive cells, immature cells, lymphocytes, monocytes, etc. Low-power microscopes are used to observe the overall fragmentation of the bone marrow.

2. Counting plate: The counting plate in the bone marrow cell counter is a precise counting area with many small grids on it, which can observe many cells at the same time under a high-power microscope. The accuracy and reliability of the counting plate are crucial to the accuracy of bone marrow cell counting.

3. Physical principle: During the bone marrow cell counting process, the bone marrow fluid is smeared, dried and fixed using physical principles to facilitate observation and counting under a microscope.

In general, the bone marrow cell counter combined with observation and counting under a microscope and counting plate can accurately evaluate the levels of various blood cells in the bone marrow and provide clinicians with information on the diagnosis, treatment and prognosis of hematological diseases.